Some injections may be given at the office, but many patients will use HCG at home on their own. Insert the needle through the rubber stopper into the fluid bottle and aspirate one 1. Remove the needle and re-insert it through the rubber stopper into the powder bottle.
Inject the fluid one cc into the powder and shake gently. Turn the bottle upside down and aspirate all of the medication back into the syringe. If you have trouble conceiving, your doctor may prescribe hCG in combination with other drugs — such as menotropins Menopur, Repronex and urofollitropin Bravelle — to boost your fertility.
Some fertility problems are due to a woman having trouble producing LH. And since LH stimulates ovulation and ovulation is necessary for pregnancy — well, hCG can often help out here. In adult men , hCG is given as an injection to treat hypogonadism, a condition that causes the body to have trouble producing the male sex hormone testosterone. A boost of hCG can stimulate production of testosterone, which can increase sperm production — and therefore, in cases where sperm count may be low, fertility.
Most men receive a dosage of 1, to 4, units of hCG injected into a muscle two to three times a week for several weeks or months. But because cold liquid can be uncomfortable going in, feel free to warm it in your hand before the injection.
Keep the powder at room temperature before use. Mix by gently rolling the vial around slowly. Draw the mixed fluid back into the syringe and point it upward.
Gently flick it until all air bubbles collect on top, and then push the plunger a little bit until the bubbles are gone. Where you inject hCG into your body depends on the instructions your doctor has given you. Your doctor may give you your first injection of hCG.
You should only inject hCG yourself if you feel completely comfortable doing so. This is good news — fat is your friend and tends to make the injection fairly painless. To do this, your doctor or pharmacist will typically give you a short gauge needle. The lower abdomen is a common injection site for hCG. Stick to the semi-circle area below your belly button and above your pubic region. Be sure to stay at least one inch away from your belly button. This makes a subcutaneous injection easier and less painful.
Choose an injection site away from your knee on the thick, outside part of your thigh. The front of your thigh will work, too. Follow the directions on your prescription label. HCG is given as an injection under the skin or into a muscle. Your doctor, nurse, or other healthcare provider will give you this injection.
You may be shown how to inject your medicine at home. Use each disposable needle only one time. Throw away used needles in a puncture-proof container ask your pharmacist where you can get one and how to dispose of it. Keep this container out of the reach of children and pets.
To be sure this medication is helping your condition, your doctor will need to check you on a regular basis. Do not miss any scheduled appointments. Some brands of HCG come in powder form with a separate liquid that you must mix together and draw into a syringe.
Other brands are provided in single-dose prefilled syringes. Do not use the medication if it has changed colors or the liquid has any particles in it. Call your doctor for a new prescription. After mixing the powder with the liquid you must keep the mixture in the refrigerator. If you are using the Pregnyl brand of HCG, throw away any mixed medicine that you have not used within 60 days after mixing. If you are using the Novarel brand of HCG, throw away any mixed medicine that you have not used within 30 days after mixing.
Store Ovidrel prefilled syringes in the refrigerator. You may also store Ovidrel at room temperature protected from light, but you must use it within 30 days. Carefully follow the mixing, storage, and expiration instructions that come with the brand of HCG you are using. Ask your doctor or pharmacist if you have questions about how long your mixed medicine can be stored and at what temperature. Seek emergency medical attention if you think you have used too much of this medicine.
An overdose of HCG is not expected to produce life-threatening symptoms. In one study, single i. These observations indicate that i. A lower bioavailability of hCG after s. Such an approach may still reach the minimum hCG threshold for final oocyte maturation in most obese patients, although the dosage may need to be individualized in extremely obese women.
Given its poor bioavailability, the s. In conclusion, the higher bioavailability of hCG after i. These findings support the advice that obese women should reduce their body weight before embarking on subfertility treatment, as the poor bioavailability of gonadotrophins is one of the many problems that these women might encounter. Figure 1. Abdalla, H. Google Scholar. Chong, A. Crosignani, P. Dobbs, K. Duijkers, I. Lashen, H. Mannaerts, B. McClure, N.
Ng, E. Saal, W. Sills, E. Stelling, J. Weissman, A. Wikland, M. WHO, Geneva, Switzerland. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide.
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